Endocrine Abstracts

Male osteoporosis is a reality and in many cases appears to be secondary to drug administration. Many pharmaceutical agents are related to the appearance of osteoporosis, affecting bone metabolism by multiple and diverse mechanisms.The aim was to describe the case of a patient who presented with male osteoporosis of multiple drug aetiology.A patient, male aged 52 years, an orthodox priest, presented with spontaneous fractures and d...

Thyroid antibodies are a heterogenous group of antibodies with diverse and partly unknown properties. The effect of these antibodies on other organ systems and especially on the renal system is unknown. There is however some evidence that thyroid, in particular thyroglobulin antibodies, may affect renal function and may cause glomerulonephritis and possibly nephrotic syndrome. Nephrotic syndrome may alter thyroxine metabolism, as it affects its renal excretion and its albumin ...

Introduction: Metastases to the thyroid are rare (1.4–3% of malignant solid tumors). When present, metastatic cancers mimic the ultrasound image of the thyroid parenchyma, hindering diagnosis. Breast cancer rarely metastasizes to the thyroid.Case: A 61-year-old woman was referred for goiterin the context of post-surgery evaluation for breast cancer. Thyrotropin (1.14 mIU/l), calcitonin (0.5 pg/ml) and parathyroidhormone (54 pg/ml) levels were norma...

Introduction: Lactation is a period of particular importance regarding the management of glycemia in women with Diabetes Mellitus type 1 (DM1), the aim being to prevent hypoglycemia during breastfeeding. The purpose of this study was to investigate the variation of insulin requirements during lactation in comparison with pre-pregnancy levels in women with DM1 and to find potential correlation factors.Materials-methods: We conducted a retrospective case f...

Introduction: Internet users perform health information-seeking searches triggered by personal symptoms or diseases. Such searches may provide information - albeit indirectly - on disease patterns and epidemiology (PLoS One. 2014, 9:e109583, PNAS 2016; 113:6689-94). It was recently reported that in Asia (more particularly in Taiwan), online searches for obesity and diet (indirectly reflecting corresponding health-seeking behaviors) at times of financial crisis (recession) were...

Introduction: Betamethasone (BM) is widely used in pregnancy. Its diabetogenic potential is known, and in combination with placental insulin resistance in pregnancy, leads to a transient increase in glycemia. Our aim was to study the changes in glycemia in women with singleton pregnancies and pre-existing diabetes mellitus, under insulin therapy, after administration of BM for obstetric causes.Materials and methods: We closely monitored and assessed the ...

Introduction: Prolactinomas are rarely found in adolescents under 15 (incidence 0.1/1.000.000). They account for 50% of all types of pituitary adenomas in childhood and adolescence (2% of intracranial tumors). The mean time from onset of symptoms to diagnosis is 2.4 years on average for girls. In cases of macroadenomas, TSH and GH deficiency may coexist. The gold standard primary therapy is dopamine agonists. In case of non-response, or the presence of large prolactinomas with...

Introduction: The role of thyroid hormones is important in testicular development and function (involvement in Sertoli cell proliferation and functional maturation control and postnatally in Leydig cell differentiation and steroidogenesis). Additionally, thyroid hormone receptors are found in testicular cells throughout development and in adulthood. Our aim was to study thyroid hormone effects on testicular function.Materials and methods: We retrospectiv...

Introduction: Exposure to air pollution and in particular to nitrogen dioxide (NO2) or particulate pollutants less than 2.5 µm (PM2.5) or 10 µm (PM10) in diameter has been linked to thyroid (dys)function in pregnant women. The environmental degradation that has occurred in recent years in the region of Athens led us to a local study of air pollution against thyroid function in pregnant women in Athens. We hypothesized that there may be a dose-effect relati...

Adrenal incidentalomas are increasingly recognized today as a result of technology use, such as computed tomography and magnetic resonance imaging. Adrenal incidentalomas are of diverse nature and their secretory activity is currently on research focus.The aim was to describe 39 consecutive patients with adrenal incidentalomas presenting over a period of 1 year.Materials and methods: A group of 39 consecutive patients with adrenal ...